Comparative study of ivermectin and permethrin 5% in treatment of scabies patients

 

Yashdeep^1*, Kishor Singh², Deepika³, Parvesh⁴, Usha Kataria⁵

 

^1,4Resident, ²Professor and HOD, Department of Dermatology, NIMS Medical College, Jaipur, Rajasthan, INDIA.

⁴Senior Resident, Dr Baba Sahib Ambedkar Medical College and Hospital, Delhi, INDIA.

5Associate Professor, Department of Dermatoogy, BPS Government Medical College, Khanpur Kalan, Sonepat, Haryana, INDIA.

Email: robinmalik53@gmail.com

 

Abstract              Scabies is an ectoparasitic, highly contagious skin disease caused by a mite called Sarcoptes scabiei. The insecticides ivermectin and permethrin are commonly used for treatment of scabies. This study aimed at comparing the efficacy of oral ivermectin with topical permethrin in treating scabies Patients were divided into two groups randomly. The first group and their family contacts received 5% permethrin cream and the other received oral ivermectin. Treatment was evaluated at intervals of 2 and 4 week. Ivermectin was found to be as effective as permethrin, it has a few advantages over topical permethrin. Both drugs are cost-effective, but ivermectin has the advantage that treatment can be given to large numbers of patients with better compliance and with or without supervision.

Key Words: scabies.