Extra-intestinal manifestations of ulcerative colitis

 

Ashish R Bhootra¹, Samil Sajal^2*, Rekha S Patil³, Y K Boliya⁴, Santosh D Hajare⁵

 

¹Consultant Physician, Metas Adventist Hospital, Surat, Gujarat, INDIA.

 

Abstract              Background: Inflammatory bowel diseases are considered as systemic diseases since they are often associated with extraintestinal manifestations. Ulcerative colitis manifestation can affect any organ system. Studies on extraintestinal involvement of UC are very few in India. In view of this context, the present study was undertaken to extraintestinal manifestations UC in a tertiary care medical center. Material and Methods: The present study was conducted in the Department of General Medicine on 35 patients over a period of two years. All cases were analyzed by clinical symptoms, laboratory investigations, colonoscopic findings and histopathological features. Clinical severity was assessed by Truewitt Love’s criteria and endoscopic grading (Baron’s criteria) was performed. Results: The peak incidence of UC was seen in 20-40 years age group. Males were more affected than females. Diarrhea and blood in stools were the most common presenting complaint. Extraintestinal manifestations were seen in 25.71% of patients. Arthritis was most common extra intestinal manifestation. Majority of patients with extraintestinal manifestations had moderate disease severity. Conclusion: There is a need of increased awareness of the high incidence of extraintestinal manifestations in UC patients for prevention, early diagnosis, and adequate treatment of these pathological conditions.

Key Words: Inflammatory bowel disease, Ulcerative colitis, extra intestinal manifestations, arthritis, severity.