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Table of Content - Volume 8 Issue 1 - October 2017
Comparison of urticaria activity score over 8 weeks in chronic idiopathic urticaria after methotrexate treatment
Ketki S Chavanda1, Ajay G Ovhal2*, Jerajani HR3, Satish Udare4
1Assistant Professor, 2Associate Professor, Department of Skin and VD, Government Medical College, Latur, Maharashtra, INDIA. 3Professor and HOD, 4Professor, Department of Dermatology, MGM institute of health sciences, Kamothe, Navi Mumbai, Maharashtra, INDIA. Email: drajayovhal@gmail.com
Abstract Background: Urticaria is a common condition observed commonly in dermatology OPD. UAS is used to assess effect of methotrexate on chronic urticaria patients. Aim and Objective: to compare Urticaria Activity Score over 8 weeks in chronic idiopathic urticaria after methotrexate treatment Methodology: Total 60 patients were studied who had history of 6 weeks or more of urticaria. Data was collected using pretested questionnaire. Data regarding detailed history, clinical examination and investigations. All patients were treated with methotrexate. Effect of methotrexate was assessed with UAS. Data was analysed with appropriate statistical tests. Results and Discussion: At the end of 8 weeks of methotrexate therapy, there was decline in the mean UAS of all the patients compared to baseline 5.97 (SD ± 1.87) and at 8 weeks 0.35 (SD± 0.57) which was statistically significant (P < 0.001) proving efficacy of the treatment. Key Words: chronic idiopathic urticaria. |
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