Official Journals By StatPerson Publication
Table of Content - Volume 11 Issue 2 - August 2019
A study on postoperative complications following major obstetrics and gynaecological surgeries
Anjum Kekhashan1*, D Sravani2, Fawad Sheikh3
1Associate Professor, 2PG Student, Department of Obstetrics and Gynaecology, Deccan College of Medical Sciences, Hyderabad, Telangana, INDIA. Email: dranjumkehkashan@gmail.com
Abstract Background: Any surgical procedure carries risks of complications. The risk of postoperative complications depends on individual characteristics, including: age, medical comorbidities, and functional status. They need to be reduced because they contribute to morbidity and mortality. Adverse events that are closely related to processes of care, such as postoperative complications, may be a better measure of quality than death rates or other intermediate out comes (1).Aim of The Study: To study incidence of post operative complications and surgical care following major obstetric and gynaecological surgeries. Objectives: 1. To know different types of post operative complications following major obstetric and gynaecological surgeries.2. To know the relative incidence of such post operative complication.3To Study factors that are associated with post operative complications such as obesity, blood loss and duration of surgery (more than or less than 02hours)Materials And Method: An observational study was conducted at Owaisi Hospital and Princess Esra hospital in the Department of Obstetrics and Gynecology from August 2016 to January 2018. The study included all the patients undergoing major surgeries for either obstetric or gynaecological indication. Results: The study focused on the post operative complications following major obstetric and gynaecological surgeries. The following are the complications observed in the present study. Overall the post operative complications observed are very low. 8.6% of total cases showed febrile morbidity, the highest recorded complication. Vault hemorrhage was 4.4% (4 of 84 patients of hysterectomy) followed by lap surgery converted to open surgery (2.3% of 129 lap surgeries). Surgical site infections are expected to be high in any surgeries but in the present study only 1.6% of the cases had developed this complication. Blood transfusion and blood loss more than 1000ml was in 1.8% of the cases. Urinary retention after open surgery and laparoscopic surgery occurred in 1.7% and 4.6%, respectively. Conclusion: The incidence of post operative complications can be reduced by 1.Proper selection of the patient2.Pre-operative evaluation of the patient3.Improve nutritional status and hygiene of the patient prior to surgery.4.Intra operatively - maintain sterility, good surgical technique, reducing blood loss and strict vigilance of unavoidable complications.5.Post operatively-adequate analgesia, fulfillment of hydration, antibiotics, starting drugs for co-morbid conditions and monitoring of patient for development of any complications. Key Word: surgical procedure.
INTRODUCTION Any surgical procedure carries risks of complications. The risk of postoperative complications depends on individual characteristics, including: age, medical comorbidities, and functional status. They need to be reduced because they contribute to morbidity and mortality. Adverse events that are closely related to processes of care, such as postoperative complications, may be a better measure of quality than death rates or other intermediate out comes (1). With preoperative evaluation, meticulous technique, and vigilance for impending problems, intra operative and early postoperative complications are largely preventable.The keys to reduce the morbidity due to post operative complications are suspicion, anticipation, early recognition and prompt appropriate intervention.These complications are not only distressing to the patients and care providers but can also impose an economic burden on hospital. It is necessary to know the incidence of each of the post operative complications, so as to standardize the assessment and prompt management, such that high quality care can be administered.
OBJECTIVES OF THE STUDY
MATERIALS AND METHODAn observational study was conducted at Owaisi Hospital and Princess Esra hospital in the Department of Obstetrics and Gynecology form august 2016 to january2018 The study included all the patients undergoing major surgeries for either obstetric or gynaecological indication.Method of collection of dataInclusion Criteria The study will included all the patients admitted in obstetrics and gynaecology ward, who underwent major surgery on elective or emergency basis. Exclusion CriteriaMinor procedures were excluded from the study. The following procedures in obstetric and gynaecology were excluded from this study. Obstetrics
Gynaecology
All cases were followed up post operatively during the period of hospital stay.
RESULTS
|
S No |
Surgery |
Count |
1 |
Emergency Primary |
147 |
2 |
Elective Primary |
08 |
3 |
Emergency repeat |
73 |
4 |
Elective Repeat |
33 |
|
Total |
261 |
Table 2: Various gynaecological surgeries
S.No |
Surgery |
Count |
1 |
Total abdominal hysterectomy |
53 |
2 |
Vaginal hysterectomy |
14 |
3 |
Staging laparotomy |
15 |
4 |
Abdominal tubectomy |
17 |
5 |
Exploratory laparotomy |
07 |
6 |
Abdominal ovarian cystectomy |
01 |
7 |
Diagnostic laparoscopy |
28 |
8 |
Lap cystectomy |
19 |
9 |
Lap sterilization |
80 |
10 |
VVF repair |
01 |
11 |
Tension free vaginal tape placement |
01 |
12 |
LAVH |
02 |
13 |
Abdominal sacrocolpopexy |
01 |
|
Total |
239 |
S.No |
Post operative complication |
Percentage N=500 (%) |
|||
1 |
Surgical site infection |
8 (1.6) |
|||
2 |
Urinary retention |
||||
a) After open surgery |
6 (1.7) |
||||
b) Laparoscopic Surgery |
5 (4.6) |
||||
3 |
UTI |
8(1.6) |
|||
4 |
Blood Transfusion( blood loss > 1000ml during surgery) |
9(1.8) |
|||
5 |
Vault Haemorrhage (post hysterectomy) |
4(4.4) |
|||
6 |
Lap. converted to open surgery |
3 (2.3) |
|||
7 |
Febrile Morbidity |
43(8.6) |
|||
8 |
Basal pneumonitis |
1(0.2) |
|||
9 |
Bladder injuries |
2(0.4) |
|||
10 |
Bowel injuries |
1(0.2) |
|||
11 |
Re exploration |
1(0.2) |
|||
12 |
Bed Sore |
2(0.4) |
|||
13
|
Nil |
407(81.4) |
|
||
|
Total |
500(100) |
|
A retrospective analysis of observations during the study was carried out. Various clinical parameters like age of patient, blood pressure, hemoglobin content, kind of surgery, post-operative complications, time taken for completion of surgery, days of hospital stay etc. were recorded systematically. These parameters have great relevance in clinical research. Most of these parameters are highly correlated with each other. The statistical procedure in the present study, chi-square analysis, tests the association between parameters and gives degree of association. Following are the results of the chi-square analysis done between important parameters.
Post-operative complications |
Haemoglobin |
Total |
p value |
|
>10 g/dl n = 451 (%) |
8.1-10 g/dl n = 49 (%) |
|
||
Blood Transfusion |
5 (1.1) |
4 (8.1) |
9 (1.8) |
0.0211* |
Febrile Morbidity |
34 (7.5) |
2 (4) |
36 (7.2) |
|
Surgical site infection(SSI) |
8 (1.8) |
1 (2) |
9 (1.8) |
|
UTI |
7 (1.6) |
1 (2) |
8 (1.6) |
|
Total |
54 (12) |
8 (16.3) |
62 (12.4) |
* Indicates significant at 5% confidence limit
The number of patients with Hemoglobin levels lower than 10 gm % were very less as pre-operatively anemia was corrected in all elective cases.
Post-operative complications |
BMI(kg/m2) |
Total
|
p value |
||
>30 n=37 (%) |
25.1 – 30 n=133 (%) |
Upto25 n=330 (%) |
|
||
Febrile Morbidity |
1(2.7) |
9(6.7) |
25(7.5) |
35(7) |
<.0001* |
Surgical site infections(SSI) |
5(13.5) |
3(2.2) |
1(0.3) |
9(1.8) |
|
Total |
6(16.2) |
12(9) |
26(7.8) |
44(8.8) |
* Indicates confidence interval significant at 1%
The two parameters, BMI and postoperative complications are significantly associated with each other (Table 2c). The present study clearly states that patients with BMI more than 30kg/sq m are likely to develop Surgical site infections
Blood loss in ml |
Duration of surgery (minutes) |
Total |
p value |
||
>120 n=16 (%) |
61-120 n=90 (%) |
Upto 60 n=394(%) |
|
||
>1000 |
5(31.2) |
1(1.1) |
1(0.2) |
7(1.4) |
<.0001* |
801 to 1000 |
1(6.25) |
2(2.2) |
3(0.7) |
6(1.2) |
|
500 to 800 |
1(6.25) |
6(6.6) |
8(2) |
15(3) |
|
300 to 500 |
4(25) |
9(10) |
198(50.2) |
211(42.2) |
|
<300 |
5(31.2) |
72(80) |
184(46.7) |
261(52.2) |
|
Total |
16(100) |
90(100) |
394(100) |
500(100) |
*Indicates significant at 1% confidence interval
A positive association exists between blood loss during operation and duration of surgery (Table 2d). As the duration increases there is high probability of more blood loss and it stands true.
Post Op Complication |
Duration of surgery (minutes) |
Total N=500 |
p value |
||
>120 n=16 (%) |
61-120 n=90(%) |
Upto 60 n=394 (%) |
|
||
Blood Transfusion |
3(18.7) |
3(3.3) |
3(0.7) |
9(1.8) |
0.0491* |
Febrile Morbidity |
0 |
12(13.3) |
23(5.8) |
35(7) |
|
Surgical site infection(SSI) |
0 |
3(3.3) |
6(1.5) |
9(1.8) |
|
Urinary retention |
2(12.5) |
4(4.4) |
4(1) |
10(2) |
|
UTI |
1(6.2) |
1(1.1) |
6(1.5) |
8(1.6) |
|
Total |
6(37.5) |
23(25.5) |
42(10.6) |
71(14.2) |
* Indicates significant at 5% confidence interval
Post operative complications are likely to be high as the duration of surgery increases (Table 2e). This explains complex surgery require more time and are associated with more complications. The duration of anaesthesia is more. Complications due to prolonged exposure of peritoneal contents to outside environment and probabilities of contamination increases. There is requirement of extra doses of antibiotics as the surgery time increases by 02 hours.
Days of hospital stay |
Count of patients with |
P value |
|
No Complications |
Post-operative complications |
||
1 |
80 |
0 |
<0.0001* |
2 |
65 |
0 |
|
3 |
44 |
0 |
|
4 |
82 |
7 |
|
5 |
93 |
10 |
|
6 |
29 |
6 |
|
7 |
12 |
29 |
|
8 |
02 |
13 |
|
10 |
04 |
18 |
|
11 |
0 |
2 |
|
12 |
0 |
3 |
|
15 |
0 |
1 |
|
Total |
411 |
89 |
*Indicates significant at 1% confidence interval
The statistical analysis shows high probability that post operative complications increases days of hospital stay. The correlation values are high suggesting that the days of hospital stay is an indicator of the complexity of post- operative complication.
Surgery |
Age (years) |
Total |
P value |
||||
>45 |
40-45 |
35-40 |
30-35 |
<30 |
|||
Abdominal tubectomy |
0 |
0 |
1 |
7 |
9 |
17 |
<0.0001* |
Diagnostic Laparoscopy |
0 |
2 |
5 |
8 |
13 |
28 |
|
Exploratory laparotomy |
0 |
0 |
0 |
1 |
6 |
7 |
|
Laparoscopic cystectomy |
0 |
0 |
5 |
4 |
10 |
19 |
|
Laproscopic sterilization |
0 |
2 |
12 |
29 |
37 |
80 |
|
LAVH |
0 |
2 |
0 |
0 |
0 |
2 |
|
LSCS |
0 |
1 |
11 |
47 |
202 |
261 |
|
Abdominal Cystectomy/Sacrocolpopexy |
0 |
1 |
0 |
0 |
1 |
2 |
|
Staging Laparotomy |
11 |
2 |
1 |
0 |
1 |
15 |
|
TAH |
20 |
27 |
6 |
0 |
0 |
53 |
|
VAH/Vaginal surgery |
14 |
2 |
0 |
0 |
0 |
16 |
|
Total |
45 |
39 |
41 |
96 |
279 |
500 |
Age and surgery are highly associated traits. It is found and is obvious that women under 30 years of age undergo maximum surgeries. Cesarean section and surgeries for contraception are the most common surgeries done among this age group. It signifies that this age is the most active reproductive age.
DISCUSSION
Post operative complications are pathologic processes that affect patients after a surgical procedure. Although some complications are minor setbacks that resolve over time, some lead to long standing disability. A detailed patient’s operative care should be planned with attention and awareness of potential complications. Intra-operative and early postoperative complications are largely preventable with preoperative evaluation, meticulous technique, and vigilance for impending problems. In the present study, of all the postoperative complications, the incidence of febrile morbidity was found to be high both in obstetric and gynaecological surgeries. However, the incidence of observed complications was considerably lower than the respective incidences quoted in the literature. In a study by Boulanger et al2 The maternal mortality rate directly associated with cesarean operation is 1.38 per 1000 surgeries. If the most minor infections are included, the infection rate for caesarean operations rises to 20.6%, whereas thrombo- embolic complications are rare at0.52%. In a study by Ozkaya et al3 on Subcutaneous clamping and cauterization for hemostasis at laparotomy with Pfannenstiel incision, Rates of surgical site infection, postoperative fever and time from skin incision to peritoneal cavity entry were significantly higher in the group with cauterization. In a study performed by Peipert JF et al4, The risk of postoperative febrile morbidity in this population was 14%. Only 50% of women received prophylactic antibiotics, whereas almost 20% received no antibiotics at all, and 30% were administered antibiotics after surgical incision. In a study by Nawaz et al5 The prevalence of bladder and ureteric injuries in obstetric surgeries was 0.25% and 0.02%, respectively. Whereas, in gynaecological surgeries the urinary bladder and ureteric injuries incidence was 0.7% and 0.6%, respectively. According to Lee et al.6 Bladder injury was the most common urological injury during obstetric and gynecologic surgery, followed by ureteral injury. Early diagnosis and urologic intervention is important for better outcomes. Mittendorf et al7 in their study with a series of 223 women who had vaginal hysterectomy, 25% were found to have vault haematoma Yuen P.M et al(8). in their study with series of 71 patients undergoing laparoscopic assisted vaginal hysterectomy, vault haemorrhage occurred in 31% of cases. Lok et al9 observed in their study that laparoscopic surgery for benign ovarian cysts, converted to laparotomy was necessary in less than 1% of patients. They concluded that careful patient selection and proper surgical training are critical to ensure safe performance of laparoscopy. In a study by Jacobsen AF et al10 the risk of DVT among healthy pregnant women undergoing elective cesarean section was low, and he recommended that general medical thrombo prophylaxis is probably not justified. Papachen et al11 in their study concluded that postoperative pulmonary complications after surgery for non-malignant gynecological disorders are infrequent but increase length of hospital stay. Sabharwal et al12 concluded in their that large bowel injuries are unfortunate complications of laparoscopic surgery, with an incidence of 0.62 to 1.6 per 1000 laparoscopies. Hakvoort et al13 in their study concluded that The risk of developing post-operative urinary retention is approximately 5% in the present general surgical population. Urinary retention after vaginal prolapse surgery occurs more frequently in women with larger cystoceles, severe intra-operative blood loss and the application of levator plication and Kelly placation. Salma et al14 in their study concluded that The indications of repeat laparotomy were secondary postpartum haemorrhage (PPH), primary PPH due to uterine atony, uterine sepsis with haemorrhage, rectus sheath haematoma, internal haemorrhage after caesarean section and abdominal wound dehiscence. In a study by Beye MD et al15 Post operative complications were represented by post-dural headaches about 5.4% and no epidural blood-patch was necessary for their management.
The incidence of post operative complications can be reduced by Proper selection of the patient Pre-operative evaluation of the patient Improve nutritional status and hygiene of the patient prior to surgery. Intra operatively - maintain sterility, good surgical technique, reducing blood loss and strict vigilance of unavoidable complications.
Post operatively-adequate analgesia, fulfillment of hydration, antibiotics, starting drugs for co-morbid conditions and monitoring of patient for development of any complications
REFERENCES