Hematological parameters in HIV/AIDS and its correlation with CD4 cell count

 

 

Abstract              Background: Promising development have been seen in recent gears in global efforts to address the AIDS epidemic, including increased access to effective treatment and prevention programmes. Hematological parameters holds key in management of HIV/AIDS cases. Objectives: To see correlation of CD4 count with different haematological parameters in HIV/AIDS patients. Material and Methods: A cross sectional study on 100 HIV subject was carried out at Bapuji Hospital and Chigateri General Hospital attached to J.J.M. Medical College,Karnataka, India during a period of 18 months. Detailed history was taken, necessary laboratory test were done. Data was analyzed using SPSS. Percentage, p value and pearson’s correlation was calculated. Results: Most common age group was found to be 31-40 age group with 57% cases, In present study 55% of female were involved as compared to 45% of male. Normocytic hypochromia was seen in 42% cases, microcytic hypochromia in 41% and dimorphism was seen in 17% cases. Also throbocytopenia was seen in 24% and leucopenia in 32% cases. 4% showed mild severity in CD4 count. Haemoglobin and blood cells were found to be significantly decreased with CD4 count. Alteration in blood urea, serum creatinine and LFT (total bilirubin, SGOT, SGPT) was not significant in my correlation studies Conclusions: There was significant correlation between CD4 and haematological profile but not in biochemical profile like LFT,KFT.

Keywords: HIV, AIDS, CD4