Study of prognostic value of glycosylated haemoglobin (HbA1C) in acute coronary syndrome in Maharashtra population

 

 

Abstract              Background: Although there are many biomarkers which have prognostic value of ACS but HbA1C is most stable and reliable method is known DM and No DM patients Method: 92 adult patients admitted in CCU, were selected their blood examination like RBS Fasting PP., serum cholesterol, HDL, LDL, HbA1C levels were studied left ventricular ejection fraction was measured by Simpsons method using 2 dimensional echocardiography using 2 dimensional echocardiography Results: 30(32.6%) patients had normal level of HbA1C(>5-6) and 62(67.3%) had higher level of HbA1C (5.7 to 6.4) ECG changes were 13(14.1%) NSTEMI 17(18.4%) STEMI in normal HbA1C patients, 18(19.5%) NSTEMI 44(47.8%) in elevated HbA1C patients, 8(8.6%) had positive, heart failure 22(23.9%) had negative, heart failure in patients in normal level of HbA1C while 15(16.3%) positive heart failure , 47(51%) negative heart failure in elevated HbA1C patients. Conclusion: HbA1C is a stable reliable prognostic biomarker in ACS patients with or without DM.

Key words: Diabetic mellitus, Acute coronary syndrome, non-ST elevation myocardial infarction, ST elevation myocardial infarction, coronary cardiac unit.