Comparative study of liver test, Haemoglobin and plasma glucose levels between alcoholic and normal individuals

 

 

Abstract              Background: Alcohol abuse is a global problem which affects families and society as a whole apart from liver functions it impairs insulin and cardiac structure and functions. Methods: 50 (fifty) alcoholic aged between 25 to 65 years were studied and compared with controlled group. Each patient underwent anthropometric, Blood pressure Hb%, FBS, PPBS, S. Bilirubin and significant parameters were noted. Results: Hypertensive patients were 11 (22%) in alcoholics, 3 (6%) in controlled. In alcoholics, 2 (4%) dyslipidemia, 2 (4%) prolapsed of inter vertebral disc, 3 (6%) were obese height of alcoholic was 164.3 (SD±5.82) t test was 3.13 p<0.001 weight of the alcohol was 58.3 (SD±2.2) and 56.8 (SD±4.30 in controlled group t test was 2.19 p<0.01. BMR and BSA were insignificant. In the Bio-chemical analysis, In alcoholic Hb% was 13.2 (SD±1.6), 3.9 (SD±0.7) in controlled, t test was -2.83 and p<0.00. In alcoholics PPBS was 117.6 (SD±11.5) 121.4 (SD±10.10 t test -1.75 p<0.04. In the comparison of liver function test, In alcoholics S. Bilirubin was 1.3 (SD±1.2) and 0.8 (SD±0.2) t test 2.90, p<0.001, In alcoholics, AST level was 80.1 (SD±40.2) and in controlled 27.1 (SD±5.5) t test -9.2 p<0.00. In alcoholics ALT level was 81.2 (SD±36.2) and 29.2 (SD±8.2) in controlled t test 9.8 p<0.01. Conclusion: This perspective study will help the physician, cardiologist and endocrinologist to predict the prognosis and treat efficiently to avoid the risk of morbidity and mortality.

Keywords: DM=Diabetes Mellitus, HTN=Hypertension, FBS=Fasting Blood, PPBS=post parandial Blood Sugar, BSA= Body Surface Area, BMI=Body Mass Index.