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Table of Content Volume 15 Issue 3 - September 2020


Prognostic significance of creatine phospokinase (CPK) levels in assessing the severity of organo phosphorus compound poisoning

 

Siddraj Wali1, Basavaraj G T2*

 

1Assistant Professor, Department of Emergency Medicine, M. R. Medical College, Sedam Road, Kalaburagi, Karnataka, INDIA.

2Assistant Professor, Department of General Medicine, 3rd Floor, Basaveshwar Teaching & General Hospital, Sedam Road, Kalaburgi, Karnataka, INDIA. 585105.

Email: drsiddrajwali@gmail.com, basavgt8@gmail.com

 

REFERENCES

  1. Chen Y, Organophosphate-induced brain damage: Mechanisms, neuropsychiatric and neurological consequences, and potential therapeutic strategies. Neurotoxicol, 33: 391–400(2012).
  2. Selvaraj T, Sudharson T. Demographic and Clinical Profile of Organophosphorus Poisoning cases in a Medical College Hospital, Tamil Nadu. Indian Journal of Forensic and Community Medicine, April-June 2016; 3(2): 124-127.
  3. Tanen DA. Organophosphorus and Carbamate Insecticides. In: Olson, K.R. (ed.), Poisoning and Drug Overdose. Lange medical books/McGraw-Hill, 5th Edn, New York, Chicago, Toronto, section II, (2007) pp: 291-295.
  4. Bazire A, Gillon E, Lockridge O et al. The kinetic study of the inhibition of human cholinesterases by demeton- S-methyl shows that cholinesterase-based titration methods are not suitable for this organophosphate. Toxicol. In Vitro 2011; 25:754-759.
  5. Bhattacharyya K, Phaujdar S, Sarkar R et al. Serum creatine phosphokinase: a probable marker of severity in organophosphorus poisoning. Toxicol. Interna 2011; 18(2):117-123.
  6. Agarwal SB, Bhatnagar VK, Agarwal A, et al. Impairment in clinical indices in acute organophosphate insecticide poisoning patients in India. The Internet J of Toxicology 2007;4(1):1-6.
  7. Hassan NAM, Madboly AG. Correlation between serum creatine phosphokinase and severity of acute organophosphorus poisoning. IOSR Journal of Environmental Science, Toxicology and Food Technology (IOSR-JESTFT) 2013:4(5):18-29.
  8. Kalyanam B, Narayana S, Kamarthy P. A rare neurological complication of acute organophosphorous poisoning. Toxicol Int 2013;20:18991.
  9. Eddleston M, Mohamed F, Davies JO, Eyer P, Worek F, Sheriff MH, et al. Respiratory failure in acute organophosphorus pesticide self-poisoning. QJM. 2006;99:513–22.
  10. Yang CC, Deng JF. Intermediate syndrome following organophosphate insecticide poisoning. J Chin Med Assoc 2007;70:46772.
  11. Bharath Kumar Guntheti, Shaik Khaja, S.S. Panda. A Study of Serum Cholinesterase Levels in Organo phosphorous Poisoning Cases. Journal of the Indian academy of forensic medicine, 2010; 32(4): 332-335.
  12. S Agarwal, V Bhatnagar, A Agarwal, U Agarwal, K Venkaiah, S Nigam, S Kashyap. Impairment in Clinical Indices in Acute Organophosphate Insecticide Poisoning Patients in India. The Internet Journal of Toxicology., 2006; 4: 1-7.
  13. Senanayake N, De Silva HJ, Karalliledde L. A scale to assess severity of organophosphorus intoxication: POP scale. Hum Exp Toxicol. 1993;12:297-99.
  14. Nermeen A. M. Hassan N, Madboly A. Correlation between Serum Creatine Phosphokinase and Severity of Acute Organophosphorus Poisoning: A Prospective Clinical Study (2012-2013). IOSR Journal Of Environmental Science, Toxicology And Food Technology. 2013 Jan 1;4:18–29.
  15. Sen R, Nayak J, Khadanga S. Study of serum cholinesterase, CPK and LDH as prognostic biomarkers in organophosphorus poisoning. International Journal of Medical Research and Review [Internet]. 2014 Jun 30. Available from: http://medresearch.in/index.php/IJMRR/article/view/101
  16. Aygun D, Erenler AK, Karatas AD, Baydin A. Intermediate syndrome following Acute Organophosphate poisoning: Correlation with initial Serum levels of Muscle Enzymes. Basic Clin Pharmacol Toxicol. 2007;100:201-4.
  17. Rode Vikram, Jadhav Nitin, Study of serum creatine phosphokinase levels as a prognostic biomarker among cases of organophosphate poisoning in a tertiary health care center, World Journal Of Pharmaceutical And Medical Research 2018,4(6), 195-203
  18. Sniderman AD. Is there value in liver function test and creatine phosphokinase monitoring with statin use. Am J Cardiol. 2004;94(9A):30F-4.