AbstracIntroduction: Neonatal morbidity and mortality rates reflect a nation’s socioeconomic status, as well as the efficiency and effectiveness of their healthcare services. Aims and Objectives: To Study Outcome in Neonatal Patients admitted to NICU of tertiary health care center. Methodology: This was a cross-sectional study carried out in the Department of Pediatrics at the tertiary health care center during the period of one year from January 2104 to January 2015 in all the Patients admitted in NICU with all causes. There were total 148 neonates were admitted to the Department for various reasons. The detail clinical history taken from the Parents of child and all necessary investigations were carried out for the Correct Diagnosis. Result: The Reason for NICU Admission were Neonatal jaundice -37.16% followed by Birth asphyxia-; 15.54%; Prematurity (Low Birth Weight) -14.86%; Septicemia-10.13%; Meconium aspiration syndrome (MAS) -6.75%; Respiratory distress syndrome (RDS)-6.08%;Hypoglycaemia-5.40%;Multiple congenital malformations-1.35%; Imperforate anus -1.35%; Hypothermia-0.67%;Intrauterine growth retardation - 0.67% The major causes of deaths in our study were Prematurity (LBW) -29.62% Followed by Neonatal septicemia-25.92%;Birth asphyxia -18.51%;RDS-7.40%; MAS-7.40%; MAS + birth asphyxia-3.70%;Multiple congenital anomalies-7.40%. Majority of the NICU admitted patients Recovered -66.89% and Death Occurred in 18.24%;8.10%-Referred to Higher Centre; 6.75% were Discharged against Medical Advice. Conclusion: In our study the Reasons for NICU Admission were Neonatal jaundice followed by Birth Asphyxia. The major causes of deaths in our study were Prematurity (LBW) Followed by Neonatal septicaemia Majority of the NICU admitted patients Recovered

Keywords: Meconium aspiration syndrome (MAS), Respiratory distress syndrome (RDS) Multiple congenital malformations, Imperforate anus, Intrauterine growth retardation, Hypothermia.