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[Abstract] [PDF] [HTML] [Linked References] MedPulse - International Medical Journal, ISSN 2348-2516 E-ISSN: 2348-1897 Volume 1, Issue 2, April 2014 pp 186-188 Research Article The comparative study between the efficacy of high dose of acyclovir and erythromycin on pityriasis rosea Kakali Mridha1, Dayamay Pal2, Sukumar Jana3 1,2Assistant Professor, 3Associate Professor, Department of Dermatology, Calcutta National Medical College, Kolkata, West Bengal, INDIA.
Abstract
Pityriasis Rosea or PR is a commonly encountered papulosquamous disorder, which is self limiting in nature. Researchers believe of its infective origin, either bacterial or viral. AIM: To compare the treatment efficacy with Erythromycin to antiviral agents Acyclovir in PR. Methods: Clinically confirm cases of PR without any contraindication to above mentioned treatment regimen were taken for study. They were divided into two groups. One group took erythromycin and another group took Aclycovir. Al the patients were examined at two, four, eight weeks of the commencement of study and followed for another few months. Results: Total 23 male, 27 females patients were successfully completed the study. After eight weeks 22 patients in Aclycovir group and 10 patients in Erythromycin group respectively showed complete response. Symptom like pruritus control faster in Aclycovir group. No cases showed any adverse drug reactions. Conclusion: Higher dose of oral Acyclovir was a safe and effective treatment for PR but age and sex matched controlled study with larger sample volume is required for confirmation of our observation. |
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