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Associate Editor's Profile


nagesh

B. NAGESHWAR RAO.  M.Sc. Ph.D

House No. 3-1-24, Old Bazar,

Mahabubabad, (Dist), 506 101,

Telengana, India.

Phone: +919032544988 (Mobile)

Email: nageshmsc@gmail.com

                                                               

SPECIFIC FIELDS WORKED IN

  • Bacteriology and Immunology,
  • Cellular & Molecular Biology,
  • Mycology, Virology and Parasitology,
  • Molecular Radiation Biology,
  • Experimental Oncology and Therapeutics,
  • Natural products - biological activity and genotoxicology,
  • Environmental Toxicology and Occupational Hazards,
  • Heavy metal toxicology

 

ACADEMIC QUALIFICATIONS

Doctor of Philosophy (Ph.D), (2011)

Life Sciences Centre, Manipal University, Manipal.

Dissertation: Preclinical studies on the antagonistic effect of Zingerone, a phenolic alkanone against gamma radiation

Master of Science (M.Sc), (1999)

 M.Sc. (Medical) Microbiology from Kasturba Medical College, Mangalore (MAHE).

Bachelor of Science (B.Sc), (1996)

Microbiology from Kakatiya University

 

TEACHING /RESEARCH EXPERIENCE

Positions held:

 

Professor of Microbiology                                  19th April 2018– Till date

Mamata Medical College,

Khammam, Telangana, India.

 

Associate Professor of Microbiology                 11th Mar 2015 – 18th April 2018

Mamata Medical College,

Khammam, Telangana, India.

Assistant Professor of Microbiology                 1st Jan. 2004 – 10th Mar 2015

Mamata Medical College, Khammam,

Andhra Pradesh, India.

Tutor/Lecturer of Microbiology                        1st Jan. 2000 – 31st Dec 2003

Mamata Medical College, Khammam,

Andhra Pradesh, India.

 

AWARDS

  • Awarded “ Young Scientist Award” at Mamata Medical College in 2015
  • Awarded Senior Research Fellowship (IRIS No. 2006-06120) by Indian Council of Medical Research (ICMR), Govt. of India, New Delhi.

LIFE MEMBERSHIPS OF PROFESSIONAL SOCIETIES

    • Indian Association for Medical Microbiologists (IAMM)
    • Indian Society for Radiation Biology (ISRB)

 

 

SCIENTIFIC TECHNIQUES ACQUAINTED WITH

  • Well experienced in reporting routine clinical microbiology investigations in the hospital laboratory at University Medical Centre (A unit of Manipal Academy of higher Education) Mangalore, India.
  • Operation of Automated Vitek system for the Bacteriological Studies and Identification.
  • Experienced in the newer methods of Microbiological investigations by ELISA techniques.
  • Experienced in the cellular biology techniques in assessing DNA damage and repair assays like FADU assay, g- H2AX foci, Comet assay and image analysis.
  • Tissue culture handling of various cell lines and primary cultures and assays like the micronuclei, chromosomal aberration assay, cell viability assays and Clonogenic survival assays in vitro.
  • Experienced in the techniques like western blotting, Flow cytometric analysis, Apoptosis assays, Immunohistochemistry, Histochemical staining and Enzyme activity assays.
  • Animal handling of mice and rats and experiments related to tumor studies with Ehrlich ascites carcinoma.
  • Human peripheral blood lymphocyte micronuclei assay and chromosomal aberration assay.
  • Mice bone marrow and splenocyte culture for micronuclei and chromosomal aberration studies.
  • Antioxidant Enzymatic studies and genotoxicity studies.

 

ASSOCIATED AND ASSISTED WITH THE FOLLOWING PROJECT WORKS

 

  • Bacteriological study of Urinary Tract Infections.
  • Isolation and Identification of Aerobic Bacterial Flora in eyes of Normal persons
  • Screening for HIV-1 and HIV-2, Antibodies by ELISA, in voluntary blood donors at district hospital in Khammam
  • A study on Antibiotic resistance among the Moraxella in Chronic Respiratory Infections.
  • Incidence of Hepatitis-C among voluntary blood donors at General Hospital in Khammam
  •  Study of osteoporosis in ovariectomized mice with Raman Spectroscopy
  • Cytoprotective and anti-genotoxic effects of flavonoids and a glucosylxanthone on cadmium induced toxicity in HEPG2 cell line
  • Study of the cytotoxic effect of Juglone, a naphthoquinone against estrogen positive and estrogen negative breast cancer cells.
  • Study of spectral changes in osteoporotic bone obtained from ovariectomised mice using fluorescence spectroscopy and validation by biochemical and histological parameters
  • Influence of Mangiferin on mercuric chloride induced genotoxicity and apoptotic cell death in human hepatoma (HepG2) cells
  • Modulation of mercuric chloride cytotoxicity by Mangiferin in human liver carcinoma (Hep G2) cells.
  • Cadmium gentoxicity and changes in antioxidant enzymes influenced by Mangiferin in Swiss Albino mice.
  • To assess the protective effect of N-acetyl cysteine towards radiation induced DNA damage and misrejoining.

 

LIST OF PUBLICATIONS

B Nageshwar Rao., et al. Symptomatic and Asymptomatic Bacteriuria in Pregnancy with Special Reference to HIV Positive Antenatal Women. EC Microbiology. 2018. 14. 5.  
B Nageshwar Rao, Jigni Pathan. Antibacterial efficacy of hydroalcoholic extract of garlic: An Invitro study. MedPulse International Journal of Microbiology. February 2018; 5(2): 11-14.
Kadammattil Ambika Vishnu, Sajankila Shyama Prasad, Prabhu Suma Rao, Bhuvanagiri Nageshwar, Rao, Bola Sadashiva Satish. Systemic Toxicity and Teratogenicity of Copper Oxide Nanoparticles and Copper Sulfate. Journal of Nanoscience and Nanotechnology, 2018; Volume 18, Number 4, 2394-2404(11).
Rao S A, Sunitha L, Nageshwar Rao B, Naik J P, Shekar V C. Efficacy of garlic extract and sodium hypochlorite on dental pulp dissolution: An in vitro study. Saudi Endod J, 2017;7:36-9
Shrikant L. Patil, Shilpa Patil, Nageshwar B. Rao and H M Somashekarappa. Immunomodulatory potential of Rutin and Quercetin in Swiss mice exposed to gamma radiation. International Journal of Biomedical and Advance Research 2017; 8(08): 310-317.
Rao A, Lakkireddy S, Nageshwar Rao B, Rao V. In vitro antimicrobial efficacy of photoactivated cow urine against enterococcus faecalis. Indian Journal of Conservative and Endodontics. 2016 Apr;1(1):13-6.
Nishan BS, Shubhankar Das, Nageshwar Rao B, Satish Rao BS. Thymol, a monoterpene phenolic derivative of cymene, abrogates mercury induced oxidative stress resultant cytotoxicity and genotoxicity in HepG2 (hepatocarcinoma) cells. Environmental Toxicology, 2015 Jul 8;30(8):968-80
Shrikant LP, Nageshwar Rao B, Somashekarappa HM, Rajashekhar KP. Antigenotoxic potential of rutin and quercetin in Swiss mice exposed to gamma radiation. Biomed J. 2014, Sep-Oct;37(5):305-13.
  1. Nageshwar Rao B, Archana PR, Kiran Aithal B, Sunil Kumar MR, Satish Rao BS, Protective effect of Zingerone, a dietary compound against radiation induced genetic damage and apoptosis in human lymphocytes. (2011). European Journal of Pharmacology, 657; 59–66.
  2. Nageshwar Rao B, Satish Rao B.S, Antagonistic effects of Zingerone (ZO), a phenolic alkanone against radiation induced cytotoxicity, genotoxicity, apoptosis and oxidative stress in Chinese hamster lung fibroblast cells growing in vitro. (2010) Mutagenesis, 25; 577–587.
  3. Nageshwar Rao B, Satish Rao B.S, Kiran aithal B, Sunil Kumar M.R, Radiomodifying and anticlastogenic effect of zingerone on Swiss albino mice exposed to whole body gamma radiation. (2009). Mutation Research, 677; 33-41.
  4. Vasudev Ballal, N. Nageshwar Rao, B. Kundabala, M. Seetharama Bhat, Satish Rao, B. S. Assessment of genotoxic effect of Maleic acid and EDTA: A comparative in vitro experimental study. (2012). Clinical Oral Investigations. 17(5):1319-1327.
  5. Sobhika Agarwala, Nageshwar Rao B, Kaivalya Mudholkar, Ridhirama Bhuwania and Satish Rao B. S, Mangiferin, a Dietary Xanthone Protects Against Mercury-Induced Toxicity in HepG2 Cells. (2012). Environmental Toxicology. 27(2): 117–127. 
  6. Archana, P. R. Nageshwar Rao, B. Satish Rao, B. S. In vivo Radioprotective Potential of Thymol, a Monoterpene Phenol Derivative of Cymene. (2011). Mutation Research, 24; 726(2): 136-145.
  7. Shubhankar Das, B. Nageshwar Rao and B. S. Satish Rao. Mangiferin attenuates methylmercury induced cytotoxicity against IMR-32, human neuroblastoma cells by the inhibition of oxidative stress and free radical scavenging potential. (2011). Chemico Biological Interactions, 193(2):129-140.
  8. Kaivalya Mudholkar, Nageshwar Rao B, Sobhika Agarwala and Satish Rao B. S, Mangiferin, a xanthone attenuates mercury chloride induced cytotoxicity and genotoxicity in HepG2 cells. (2011). Journal of Biochemical and Molecular Toxicology, 25(2):108-116.
  9. Kiran Aithal B, Sunil Kumar M R, Nageshwar Rao B, Raghavendra Upadhya, Vijendra Prabhu, Gopal Shavi, Karthik Arumugam, Shyam Prasad S, Udupa N, Satyamoorthy K, Satish Rao B S. Evaluation of pharmacokinetic, biodistribution, pharmacodynamic and toxicity profile of free juglone and its sterically stabilized liposomes. (2011). Journal of Pharmaceutical Sciences, 7, 1–12.
  10. Archana PR, Nageshwar Rao B, Satish Rao B.S. Modulation of gamma-ray-induced genotoxic effect by Thymol, a monoterpene phenol derivativeof cymene. (2011). Integrative Cancer Therapies. 10(4); 374-383.
  11. Vijendra Prabhu, Satish B.S. Rao, Nageshwara Rao B, Kiran B. Aithal, Pramod Kumar, and Krishna K. Mahato. Development and evaluation of an optical fibre-based helium-neon laser irradiation system for tissue regeneration: A pilot study. (2010). PRAMANA, Journal of Physics. 75: 1287–1293.
  12. Vijendra Prabhu, Satish B.S. Rao, Nageshwar Rao B, Kiran B. Aithal, Pramod Kumar, and Krishna K. Mahato, Development and Evaluation of Fiber Optic Probe Based Helium-Neon (He-Ne) Low Level Laser Therapy Set Up for Tissue Regeneration - An In vivo Experimental Study. (2010). Photochemistry and Photobiology. 86; 1364–1372.
  13. Satish Rao B. S, Nageshwar Rao B, Archana PR, Prerana Shetty. Antioxidant and radiation antagonistic effect of hydroalcoholic bark extract of Saraca indica and possible mechanism of radiation protection. (2010). Journal of Environmental Pathology, Toxicology and Oncology. 29(1):59–69.
  14. Kiran Aithal B, Sunil Kumar M.R, Nageshwar Rao B, Nayanabhirama Udupa, Satish Rao B.S, Tumor growth inhibitory effect of juglone and its radiation sensitizing potential: in vivo and in vitro studies. (2010). Integrative Cancer Therapies. 11(1): 68–80.
  15. Kasi Viswanadh. E, Nageshwar Rao. B, Satish Rao B. S. Antigenotoxic effect of Mangiferin and changes in antioxidant enzyme levels of Swiss albino mice treated with Cadmium chloride. (2010). Human & Experimental Toxicology. 29(5); 409–418.
  16. Vasudev Ballal, Kundabala M, Seetharama Bhat, Nageshwar Rao B, Satish Rao B. S, A comparative In Vitro. Evaluation of Cytotoxic effects of EDTA and Maleic acid: Root canal Irrigants. (2009). Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontology. 108; 633-638.
  17. Sunil Kumar M Rayabandla, Kiran Aithal, Nageshwar Rao Bhuvanagiri, Udupa Nayanabhirama, Satish Rao Bola Sadashiva, Cytotoxic, genotoxic and oxidative stress induced by 1, 4 - naphthoquinone in B16F1 melanoma tumor cells. (2009). Toxicology in Vitro. 23; 242–250.
  18. Satish Rao BS, Shanbhoge R, Nageshwar Rao B, Adiga SK, Upadhya D, Kiran Aithal B and Sunil Kumar MR. Preventive efficacy of hydroalchoholic extract of Cymbopogon citratus against radiation induced DNA damage on V79 cells and free radical scavenging ability against radicals generated in vitro. (2009). Human & Experimental Toxicology. 28:195–202
  19. Satish Rao BS, Sreedevi MV and Nageshwar Rao B, Cytoprotective and Antigenotoxic potential of Mangiferin, a glucosylxanthone against Cadmium chloride induced toxicity in HepG2 cells. (2009). Food and Chemical Toxicology, 47; 92- 600.
  20. Kiran Aithal B, Sunil Kumar MR, Nageshwar Rao B, Udupa N, Satish Rao BS. Juglone, a naphthoquinone from walnut exerts cytotoxic and genotoxic effects against melanoma cells: An in vitro study. (2009). Cell Biology International. 33(10):1039-1049.
  21. Archana PR, Nageshwar Rao B, Mamatha Ballal, Satish Rao B. S, Thymol, a naturally occurring monocyclic phenolic compound protects Chinese hamster lung fibroblasts from radiation induced oxidative stress and cytotoxicity. (2009). Mutation Research. 680; 70–77.
  22. Shavial Rao K, Priya Rao S, Nageshwara Rao B. Preliminary investigation of the radiosensitizing activity of guduchi (Tinospora cordifolia) in tumor-bearing mice. (2008). Phytotherapy Research. 22(11):1482-1489
  23. Jagetia GC, Ganapathi NG, Venkatesh P, Nageshwar Rao B, Baliga MS. Evaluation of the radioprotective effect of Liv 52 in mice. (2006). Environmental Molecular Mutagensis. 47(7):490-502.

LIST OF CONFERENCE/SYMPOSIUM ATTENDED

 

  • B. Nageshwar Rao, Understanding and Implimenting outcome based education OBE work shop – MAHSA University, Kulala Lumpur, Malaysia April 2013.
  • B. Nageshwar Rao and B. S. Satish Rao: Radiomodifying and anticlastogenic potential of zingerone presented at the International Conference on Radiation Biology & Translational Research on Radiation Oncology held at Jaipur from Nov. 10-12, 2008.
  • B. Nageshwar Rao, M.S. Baliga, Ponemone Venkatesh, Rosi Reddy, J.N. Ulloor and G.C. Jagetia : Abana, a polyherbal rasayana protects against radiation-induced mortality presented at the International Conference on Free Radicals and Antioxidants in Health, disease and radiation and Annual Conference of Society for Free Radical Research - India (SFRR) held at Kolkatta from  Jan. 16-18, 2006.
  • B. Nageshwar Rao and G.C. Jagetia: Liv 52, a poly herbal extract protects mouse against the radiation-induced lethality presented at the International conference on Low Dose Radiation Effects on Human Health held at Varanasi from Nov. 20-22, 2006.
  • Participated in “1st ISRB Workshop on Application of Advanced Techniques in Biomedical Research at the Department of Radiobiology”, Kasturba Medical College, Manipal, 23rd May to 4th June 2005.
  • Participated in the “XXII National Congress of Indian Association of Medical Microbiologists” held at Manipal in November 19998.
  • Participated in a work shop on “Rapid Diagnostic Tests in Medical Microbiology with special emphasis on HIV and Tuberculosis” at National conference of Association of Microbiologists of India, December 1998, Mangalore, India.

 

 

REFERENCES

 

1. Dr. B.S. Satish Rao

Professor and Head,

Division of Radiobiology & Toxicology,

Manipal Life Sciences Centre,

Manipal University, Manipal-576104,

Karnataka, India, Tel:  +919901201982, Fax: +91-820-2571919

Email: satishraomlsc@gmail.com (or) rao.satish@manipal.edu

 

2. Dr. M. S. Valiathan

National Research Professor

Manipal University, Manipal - 576 104

Karnataka, India.

 Phone: +918202922342, 2571201 Ext. 22342 (O)

+918202570491 (R); +918202571919 (Fax)

Email: msvaliathan@gmail.com (or) ms.valiathan@manipal.edu

 

3. Dr. K. Koteshwer Rao

Dean,

Mamata Medical College and General Hospital,

4-2-161, Opp. Rotary Nagar,

Khammam- 507002,

Telengana, India. Mobile: +91-9849490524

Email: drkkrao@hotmail.com